PRRT is a patient-friendly treatment of NET. NETs are rare and every NET is different. For a treatment with good results it is important that you choose a specialist who has large experience and specific knowledge in this field.
The PRRT Treatment Center Rotterdam is internationally accredited by the international association of neuroendocrine tumor specialists ENETS. Per year we treat around 100 patients from the Netherlands and abroad with positive results.
The choice of the right treatment depends on your personal situation.
Choice of Treatment
When a cure is no longer possible, the treatment focuses on lengthening life and improving the quality of life. Which treatment fits best depends on your personal situation.
Besides the grade of the NET, the choice of treatment is also dependent on:
- your general state of health;
- the growth rate of the tumor and metastases;
- the place in the body where the NET developed;
- the size of the tumors;
- the type of hormone that the NET produces.
Explanation PRRT treatment
The “standard” PRRT treatment in principle consists of 4 treatments with intervals of 6 to 12 weeks. In exceptional cases, the treatment might need to be delayed or terminated.
The treatments take place on Thursday. Patients are admitted until Friday afternoon. This is due to legislation regarding the exposure to radioactivity of members of the public other than patients. Sometimes the treatment takes place on Tuesday with a discharge on Wednesday. As radioactivity is used in PRRT, you will be admitted to the Nuclear Medicine Department at the hospital.
Day of Treatment
Patients are given an intravenous cannula on the day of treatment. Generally, blood samples are taken and other checks are carried out in the weeks or day preceding the treatment. Generally 8 patients are treated simultaneously. First, the patient receives medication against possible nausea. Then the treatment is started with a solution containing amino acids. This solution serves to reduce the amount of radiation to the kidneys.
The administration of the actual lutetium octreotate starts half an hour after the start of the amino acids, and lasts for about half an hour. The administration of the amino acid solution is then continued for another three hours. The intravenous acces is removed afterwards.
Hospital Stay and Discharge
Following the above-mentioned legislation, patients must stay one night and cannot receive visitors. The next morning they are scanned to determine whether the radioactivity has been absorbed well by the tumors, and a brief evaluation with the physician takes place.
The patients are discharged in the afternoon. The radiation still present in the body is always measured first. With this measurement the duration of the rules to be followed after treatment is determined. A travel declaration can be prepared for international patients if necessary.
Here you will find an infographic of the treatment. You can easily forward it to family or friends.